Carbazole modified oligonucleotides: synthesis, hybridization studies and fluorescence properties-Reference-Cited by-同舟云学术

Carbazole modified oligonucleotides: synthesis, hybridization studies and fluorescence properties

Published:2020 Issue:35 Volume:18 Page:6935-6948
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gouda Alaa S.¹²³⁴⁵^ORCID,Przypis Łukasz⁶⁷⁸⁹^ORCID,Walczak Krzysztof⁶⁷⁸⁹^ORCID,Jørgensen Per T.¹²³⁴⁵^ORCID,Wengel Jesper¹²³⁴⁵^ORCID

Affiliation:

1. Biomolecular Nanoscale Engineering Center

2. Department of Physics

3. Chemistry and Pharmacy

4. University of Southern Denmark

5. 5230 Odense M

6. Department of Organic Chemistry

7. Biochemistry and Biotechnology

8. Silesian University of Technology

9. Poland

Abstract

Investigation of a modified carbazole as a nucleoside mimetic and its binding affinity towards complementary DNA/RNA models shows improved thermal stability and fluorescence emission of carbazole probe–target hybrid duplexes.

Funder

Villum Fonden

Horizon 2020 Framework Programme

Politechnika Śląska

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01553A

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