Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells-Reference-Cited by-同舟云学术

Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells

Published:2021 Issue:47 Volume:11 Page:29164-29177
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lafi Zainab¹²,Alshaer Walhan³^ORCID,Hatmal Ma'mon M.⁴,Zihlif Malek⁵,Alqudah Dana A.³,Nsairat Hamdi⁶^ORCID,Azzam Hanan⁷,Aburjai Talal⁸,Bustanji Yasser⁹,Awidi Abdalla³¹⁰¹¹

Affiliation:

1. Faculty of Pharmacy, The Middle East University, Amman, Jordan

2. Department of Clinical Pharmacy, Faculty of Pharmacy, The University of Jordan, Amman 11942, Jordan

3. Cell Therapy Center, The University of Jordan, Amman 11942, Jordan

4. Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa 13133, Jordan

5. Department of Pharmacology, Faculty of Medicine, The University of Jordan, Amman 11942, Jordan

6. Pharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman 19328, Jordan

7. HMCSR, The University of Jordan, Amman 11942, Jordan

8. Department of Pharmaceutical Sciences, Faculty of Pharmacy, The University of Jordan, Amman 11942, Jordan

9. Department of Basic Medical Sciences, College of Medicine, University of Sharjah, Sharjah 27272, UAE

10. Department of Internal Medicine, Faculty of Medicine, The University of Jordan, Amman 11942, Jordan

11. Department of Hematology and Oncology, Jordan University Hospital, The University of Jordan, Amman 11942, Jordan

Abstract

Echinomycin was loaded into PEGylated pH-sensitive liposomes and functionalized with anti-nucleolin aptamer for selective targeting and pH-responsive release of echinomycin into cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05138E

Reference54 articles.

1. Echinomycin binding to the sequence CG(AT)nCG alters the structure of the central AT region

2. Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies

3. In vitro and in vivo activities of echinomycin against clinical isolates of Staphylococcus aureus

4. Echinomycin biosynthesis

5. Echinomycin Binding Sites on DNA

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