Transamidation of N-acyl-glutarimides with amines

Author:

Liu Yongmei12345,Achtenhagen Marcel5678ORCID,Liu Ruzhang1234ORCID,Szostak Michal5678ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Yangzhou University

3. Yangzhou 225002

4. China

5. Department of Chemistry

6. Rutgers University

7. Newark

8. USA

Abstract

Herein, we report a new method for transamidation of N-acyl-glutarimides with amines under mild, metal-free conditions that relies on amide bond twist to weaken amidic resonance.

Funder

National Science Foundation

National Natural Science Foundation of China

Rutgers, The State University of New Jersey

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference83 articles.

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