Synthesis of 2,6-trans- and 3,3,6-trisubstituted tetrahydropyran-4-ones from Maitland–Japp derived 2H-dihydropyran-4-ones: a total synthesis of diospongin B-Reference-Cited by-同舟云学术

Synthesis of 2,6-trans- and 3,3,6-trisubstituted tetrahydropyran-4-ones from Maitland–Japp derived 2H-dihydropyran-4-ones: a total synthesis of diospongin B

Published:2016 Issue:28 Volume:14 Page:6840-6852
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Clarke Paul A.¹²³⁴^ORCID,Nasir Nadiah Mad¹²³⁴,Sellars Philip B.¹²³⁴,Peter Alejandra M.¹²³⁴,Lawson Connor A.¹²³⁴,Burroughs James L.¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of York

3. York

4. UK

Abstract

6-Substituted-2H-dihydropyran-4-ones can be transformed into 2,6-trans- and 3,3,6-trisubstituted tetrahydropyrans via conjugate addition and electrophilic trapping.

Funder

University of York

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01182A

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