Protein crystal occurrence domains in selective protein crystallisation for bio-separation

Author:

Li Xiaoyu12345,Chen Wenqian12345ORCID,Yang Huaiyu12345ORCID,Yang Zhongqiang6789ORCID,Heng Jerry Y. Y.12345ORCID

Affiliation:

1. Department of Chemical Engineering

2. Imperial College London

3. South Kensington Campus

4. London

5. UK

6. Department of Chemistry

7. Tsinghua University

8. Beijing 100084

9. PR China

Abstract

Bio-separation is a key bottleneck in the manufacture of biopharmaceuticals.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Reference37 articles.

1. Biopharmaceutical benchmarks 2018

2. L. M. B. Intelligence , http://www.lamerie.com

3. J. A. V. Costa , H.Treichel , L. O.Santos and V. G.Martins , Chapter 16 - Solid-State Fermentation for the Production of Biosurfactants and Their Applications, in Current Developments in Biotechnology and Bioengineering , ed. A. Pandey , C. Larroche and C. R. Soccol , Elsevier , 2018 , pp. 357–372

4. Protein a chromatography at high titers

5. Recent advances in large-scale production of monoclonal antibodies and related proteins

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