Synthesis and assessment of 4-aminotetrahydroquinazoline derivatives as tick-borne encephalitis virus reproduction inhibitors-Reference-Cited by-同舟云学术

Synthesis and assessment of 4-aminotetrahydroquinazoline derivatives as tick-borne encephalitis virus reproduction inhibitors

Published:2015 Issue:11 Volume:13 Page:3406-3415
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sedenkova Kseniya N.¹²³⁴⁵,Dueva Evgenia V.¹²³⁴⁶,Averina Elena B.¹²³⁴⁵,Grishin Yuri K.¹²³⁴,Osolodkin Dmitry I.¹²³⁴⁶^ORCID,Kozlovskaya Liubov I.⁶⁷⁴,Palyulin Vladimir A.¹²³⁴⁵,Savelyev Evgenii N.⁸⁹⁴,Orlinson Boris S.⁸⁹⁴,Novakov Ivan A.⁸⁹⁴,Butov Gennady M.⁸⁹⁴,Kuznetsova Tamara S.¹²³⁴,Karganova Galina G.⁶⁷⁴¹⁰²,Zefirov Nikolay S.¹²³⁴⁵

Affiliation:

1. Department of Chemistry

2. Lomonosov Moscow State University

3. Moscow 119991

4. Russia

5. Institute of Physiologically Active Compounds

6. Chumakov Institute of Poliomyelitis and Viral Encephalitides

7. Moscow 142782

8. Volgograd State Technical University

9. Volgograd

10. Department of Biology

Abstract

A versatile synthesis of 4-aminopyrimidine N-oxides is developed and applied to obtain anti-TBEV agents.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C4OB02649G

Reference44 articles.

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2. Tick-borne encephalitis virus – a review of an emerging zoonosis

3. Neuroinvasive flavivirus infections

4. T. C. Pierson and M. S.Diamond, in Fields Virology, ed. D. M. Knipe and P. Howley, Lippincott Williams & Wilkins, Philadelphia, 6th edn, 2013, ch. 26, pp. 747–794

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