Degradation of mirubactin to multiple siderophores with varying Fe(<scp>iii</scp>) chelation properties-Reference-Cited by-同舟云学术

Degradation of mirubactin to multiple siderophores with varying Fe(iii) chelation properties

Published:2022 Issue:25 Volume:20 Page:5066-5070
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pu Hong¹²^ORCID,Jiang Ting¹²,Peng Dian³,Xia Juanjuan³,Gao Juan⁴,Wang Yeji¹,Yan Xiaohui⁵,Huang Xueshuang²,Duan Yanwen¹⁶⁷,Huang Yong¹⁷^ORCID

Affiliation:

1. Xiangya International Academy of Translational Medicine, Central South University, Changsha, Hunan, 410013, P. R. China

2. Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, Hunan, 418000, P. R. China

3. School of Pharmacy, Changsha Health Vocational College, Changsha, Hunan, 410100, P. R. China

4. School of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan, 410017, P. R. China

5. Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, P. R. China

6. Hunan Engineering Research Center of Combinatorial Biosynthesis and Natural Product Drug Discover, Changsha, Hunan, 410011, P. R. China

7. National Engineering Research Center of Combinatorial Biosynthesis for Drug Discovery, Changsha, Hunan, 410011, P. R. China

Abstract

Three siderophores mirubactins B–D (4–6) were identified as the degradation products of previously isolated mirubactin (1) and 4 contains an unusual cyclic amidine functionality. Cyclic voltammetry showed that 5 and 6 have reduced iron complexing capacity.

Funder

Natural Science Foundation of Hunan Province

The Chinese Ministry of Education 111 Project under Grant

Fundamental Research Funds for Central Universities of the Central South University

Hunan University of Medicine High-Level Talent Introduction Startup Funds

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00942K