Discovery of new cocrystals beyond serendipity: lessons learned from successes and failures-Reference-Cited by-同舟云学术

Discovery of new cocrystals beyond serendipity: lessons learned from successes and failures

Published:2024 Issue:11 Volume:26 Page:1505-1526
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Wong Si Nga¹²,Fu Minqi¹²,Li Si¹²,Kwok Wan Tung Candice¹³,Chow Stephanie¹,Low Kam-Hung⁴^ORCID,Chow Shing Fung¹²^ORCID

Affiliation:

1. Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, L2-08B, Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong, SAR, China

2. Advanced Biomedical Instrumentation Centre, Hong Kong Science Park, Shatin, Hong Kong, SAR, China

3. Leslie Dan Faculty of Pharmacy, The University of Toronto, Toronto, Ontario, Canada

4. Department of Chemistry, Faculty of Science, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China

Abstract

A holistic understanding of reaction kinetics, the presence of catalysts, and annealing conditions can advance and accelerate the screening of elusive cocrystals, expediting the development of novel drug cocrystals for future clinical use.

Funder

University Research Committee, University of Hong Kong

Innovation and Technology Fund

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CE/D4CE00021H

Reference187 articles.

1. Engineering Molecular Crystals: Backbreaking, yet Gratifying

2. Über die Dissociationswärme und den Einfluss der Temperatur auf den Dissociationsgrad der Elektrolyte

3. Rotational Dynamics of Diazabicyclo[2.2.2]octane in Isomorphous Halogen-Bonded Co-crystals: Entropic and Enthalpic Effects

4. Phase diagram and nucleation kinetics of barbituric acid – Urea Co-crystal: Focus on metastable zone width and activation energy

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