Dietary bitter ginger-derived zerumbone improved memory performance during aging through inhibition of the PERK/CHOP-dependent endoplasmic reticulum stress pathway-Reference-Cited by-同舟云学术

Dietary bitter ginger-derived zerumbone improved memory performance during aging through inhibition of the PERK/CHOP-dependent endoplasmic reticulum stress pathway

Published:2024 Issue: Volume: Page:
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yang Chuan¹²³,Zhao Meihuan¹²³,Chen Yuanyuan¹²³,Song Juxian¹²³,Wang Dan²⁴,Zou Mi²⁴,Liu Jingru⁵,Wen Wen¹²³,Xu Shijun¹²³^ORCID

Affiliation:

1. State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China

2. Institute of Materia Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China

3. School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China

4. School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China

5. University College London, Gower Street, London WC1E 6BT, UK

Abstract

Zerumbone rescued aging-related cognitive deficits (ARCD) through inhibiting the PERK/CHOP-dependent excessive endoplasmic reticulum (ER) stress.

Funder

Applied Basic Research Program of Sichuan Province

Chengdu University of Traditional Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00402G

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4. Dietary neoagarotetraose extends lifespan and impedes brain aging in mice via regulation of microbiota-gut-brain axis