New N-acyl- as well as N-phosphonoylmethyl- and N-phosphinoylmethyl-α-amino-benzylphosphonates by acylation and a tandem Kabachnik

New N-acyl- as well as N-phosphonoylmethyl- and N-phosphinoylmethyl-α-amino-benzylphosphonates by acylation and a tandem Kabachnik–Fields protocol

Published:2023 Issue:8 Volume:21 Page:1709-1718
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Varga Petra Regina¹^ORCID,Karaghiosoff Konstantin²^ORCID,Sári Éva Viktória¹,Simon András³,Hegedűs László¹^ORCID,Drahos László⁴^ORCID,Keglevich György¹^ORCID

Affiliation:

1. Department of Organic Chemistry and Technology, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary

2. Department Chemie, Ludwig-Maximilians-Universitat München, Butenandtstr. 5-13, D-81377 München, Germany

3. Department of Inorganic and Analytical Chemistry, Budapest University of Technology and Economics, 1521 Budapest, Hungary

4. MS Proteomics Research Group, Research Centre for Natural Sciences, 1117 Budapest, Hungary

Abstract

New derivatives were synthesized by the acylation of α-amino-benzylphosphonates, and by reacting them in a second Kabachnik–Fields condensation.

Funder

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00010A

Reference54 articles.

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3. Recent synthesis of aminophosphonic acids as potential biological importance

4. Methods for synthesis of N-heterocyclyl/heteroaryl- α-aminophosphonates and α-(azaheterocyclyl)phosphonates

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