Pyridine tetrafluoro-λ6-sulfanyl chlorides: spontaneous addition to alkynes and alkenes in the presence or absence of photo-irradiation

Author:

Niina Kiyoteru1234,Tanagawa Kazuhiro1234,Sumii Yuji1234ORCID,Saito Norimichi56784,Shibata Norio12349ORCID

Affiliation:

1. Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry

2. Nagoya Institute of Technology

3. Nagoya 466-8555

4. Japan

5. Pharmaceutical Division

6. Ube Industries

7. Ltd

8. Tokyo 105-8449

9. Institute of Advanced Fluorine-Containing Materials

Abstract

A radical addition reaction of Py-SF4Cl to alkynes and alkenes provide pyridine-SF4-alkenes and pyridine-SF4-alkanes under blue LED light irradiation or absence of light irradiation in CPME or without solvent.

Funder

Asahi Glass Foundation

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference64 articles.

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2. Pyridines: From Lab to Production , ed. E. F. V. Scriven , Academic Press , Oxford, UK; Waltham, MA, USA , 1st edn, 2013

3. J. Dinges and C.Lamberth , Bioactive Heterocyclic Compound Classes , Wiley-VCH , Weinheim , 2012

4. J. X. Qiao , Heterocyclic Chemistry in Drug Discovery , Wiley , Hoboken , 2013

5. The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

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