Quercetin ameliorates celiac-related intestinal inflammation caused by wheat gluten through modulating oxidative stress, Th1/Th2/Treg balance, and intestinal microflora structure

Author:

Yu Tian123ORCID,Xie Yiting123,Wang Zhongliang123,Li Jingjing123,Shen Yunpeng123,Yuan Juanli14,Gao Jinyan3,Fakruddin Md.5,Wu Yong12ORCID,Chen Hongbing12ORCID

Affiliation:

1. State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang 330047, Jiangxi, China

2. Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, Jiangxi, China

3. School of Food Science and Technology, Nanchang University, Nanchang 330031, Jiangxi, China

4. School of Pharmaceutical Science, Nanchang University, Nanchang 330006, Jiangxi, China

5. Department of Biochemistry and Microbiology, North South University, Bashundhara, Dhaka 1229, Bangladesh

Abstract

Quercetin could play a crucial role in intervening in celiac pathogenesis, not only owing to its antioxidant properties, but also because it modulates immune cell function and the intestinal microflora structure.

Funder

International Science and Technology Cooperation Programme

Publisher

Royal Society of Chemistry (RSC)

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