Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections-Reference-Cited by-同舟云学术

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

Published:2021 Issue:4 Volume:6 Page:330-340
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Kim Byungji¹²³⁴^ORCID,Yang Qinglin¹²³⁴,Chan Leslie W.⁵⁴^ORCID,Bhatia Sangeeta N.⁵⁴^ORCID,Ruoslahti Erkki⁶⁷³⁴,Sailor Michael J.¹²³⁴⁸^ORCID

Affiliation:

1. Materials Science and Engineering Program

2. University of California

3. La Jolla

4. USA

5. Massachusetts Institute of Technology

6. Cancer Research Center

7. Sanford Burnham Prebys Medical Discovery Institute

8. Department of Chemistry and Biochemistry

Abstract

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

Funder

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NH/D0NH00624F

Reference54 articles.

1. Origins and Evolution of Antibiotic Resistance

2. Platforms for antibiotic discovery

3. Resistance to antibiotics targeted to the bacterial cell wall

4. The Effect of Lipopolysaccharide Core Oligosaccharide Size on the Electrostatic Binding of Antimicrobial Proteins to Models of the Gram Negative Bacterial Outer Membrane

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