Nanoscale characterization illustrates the cisplatin-mediated biomechanical changes of B16-F10 melanoma cells-Reference-Cited by-同舟云学术

Nanoscale characterization illustrates the cisplatin-mediated biomechanical changes of B16-F10 melanoma cells

Published:2016 Issue:10 Volume:18 Page:7124-7131
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Kung Mei-Lang¹²³⁴,Hsieh Chiung-Wen¹²³⁴,Tai Ming-Hong⁵²³⁴⁶,Weng Chien-Hui⁵²³⁴,Wu Deng-Chyang⁷⁸⁹⁴¹⁰,Wu Wen-Jeng⁷⁸⁹⁴¹¹,Yeh Bi-Wen⁷⁸⁹⁴¹²,Hsieh Shu-Ling¹³¹⁴¹⁵⁴,Kuo Chao-Hung⁷⁸⁹⁴¹⁰,Hung Huey-Shan¹⁶¹⁷¹⁸⁴¹⁹,Hsieh Shuchen¹²³⁴⁷

Affiliation:

1. Department of Chemistry

2. National Sun Yat-sen University

3. Kaohsiung 80424

4. Taiwan

5. Department of Biological Sciences

6. Institute of Biomedical Sciences

7. Center for Stem Cell Research

8. Kaohsiung Medical University

9. Kaohsiung 80708

10. Division of Gastroenterology

11. Graduate Institute of Medicine

12. Department of Urology

13. Department of Seafood Science

14. National Kaohsiung Marine University

15. Kaohsiung 80811

16. Graduate Institute of Basic Medical Science

17. China Medical University

18. Taichung 40402

19. Center for Neuropsychiatry

Abstract

Cisplatin reshapes spindle-like B16-F10 cells by altering their biomechanical properties, activating FAK/Src focal adhesion signaling, and reorganizing the cytoskeleton.

Funder

Kaohsiung Medical University

National Sun Yat-sen University

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CP/C5CP07971C

Reference55 articles.

1. Cisplatin (cis-diamminedichloroplatinum II)

2. Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities

3. DNA Damage Induced by Alkylating Agents and Repair Pathways

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