A synthetic biology and green bioprocess approach to recreate agarwood sesquiterpenoid mixtures

Author:

Gutiérrez Sergio1ORCID,Overmans Sebastian1ORCID,Wellman Gordon B.1ORCID,Samaras Vasilios G.2ORCID,Oviedo Claudia34ORCID,Gede Martin35ORCID,Szekely Gyorgy345ORCID,Lauersen Kyle J.1ORCID

Affiliation:

1. Bioengineering Program, Biological, Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia

2. Analytical Chemistry Core Lab (ACL), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia

3. Advanced Membranes and Porous Materials Center (AMPM), Physical Science and Engineering Division (PSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia

4. Environmental Science and Engineering Program, Biological, Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia

5. Chemical Engineering Program, Physical Science and Engineering Division (PSE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia

Abstract

We show terpene diversity of endangered agarwoods, engineering a sustainable green algal host for terpene production, and a terpene ‘milking’ bioprocess coupled to green-chemistry functionalisation to produce terpenes like those found in agarwood.

Funder

King Abdullah University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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