Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives
Author:
Affiliation:
1. Scripps Institution of Oceanography
2. University of California
3. San Diego, La Jolla
4. USA
5. Department of Chemistry and Biochemistry
6. Skaggs School of Pharmacy and Pharmaceutical Sciences
Abstract
Interrogating the bioactivities and enzymatic modification potential of a focused library of novel synthetic thiotetronate compounds.
Funder
National Institutes of Health
Natural Sciences and Engineering Research Council of Canada
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB03109F
Reference45 articles.
1. Fix the antibiotics pipeline
2. Structure−Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
3. Synthesis and medicinal chemistry of selected antitubercular natural products and natural product derivatives
4. Bacterial Fatty Acid Biosynthesis: Targets for Antibacterial Drug Discovery
5. Inhibition of β-Ketoacyl-Acyl Carrier Protein Synthases by Thiolactomycin and Cerulenin
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