Hybrid red blood cell membrane coated porous silicon nanoparticles functionalized with cancer antigen induce depletion of T cells-Reference-Cited by-同舟云学术

Hybrid red blood cell membrane coated porous silicon nanoparticles functionalized with cancer antigen induce depletion of T cells

Published:2020 Issue:58 Volume:10 Page:35198-35205
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Rahikkala Antti¹²³⁴⁵^ORCID,Fontana Flavia¹²³⁴⁵,Bauleth-Ramos Tomás⁶⁷⁸⁹¹⁰,Correia Alexandra¹²³⁴⁵,Kemell Marianna¹¹⁴⁵¹²^ORCID,Seitsonen Jani¹³¹⁴¹⁵¹²,Mäkilä Ermei¹⁶¹⁷¹⁸¹⁹¹²,Sarmento Bruno²⁰²¹²²²³⁹^ORCID,Salonen Jarno¹⁶¹⁷¹⁸¹⁹¹²,Ruokolainen Janne¹³¹⁴¹⁵¹²,Hirvonen Jouni¹²³⁴⁵,Santos Hélder A.¹²³⁴⁵^ORCID

Affiliation:

1. Drug Research Program

2. Division of Pharmaceutical Chemistry and Technology

3. Faculty of Pharmacy

4. University of Helsinki

5. Helsinki

6. Instituto de Investigação e Inovação em Saúde (I3S)

7. University of Porto

8. Porto

9. Portugal

10. Instituto de Engenharia Biomédica (INEB)

11. Department of Chemistry

12. Finland

13. Nanomicroscopy Center

14. Aalto University

15. Espoo

16. Laboratory of Industrial Physics

17. Department of Physics

18. University of Turku

19. Turku

20. CESPU

21. Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde

22. Instituto Universitário de Ciências da Saúde

23. 4585-116 Gandra

Abstract

We report a study on the effect of red blood cell membrane based cancer antigen-functionalized nanoparticles on peripheral blood T cells. These nanoparticles induce apoptosis of T cells and they may have use in treating autoimmune diseases.

Funder

Suomen Kulttuurirahasto

Sigrid Juséliuksen Säätiö

Helsingin Yliopisto

H2020 European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA05900E

Reference53 articles.