One-pot, efficient synthesis of fused quinoline analogues <i>via</i> room temperature C(sp<sup>3</sup>)–N cleavage/aromatization reaction-Reference-Cited by-同舟云学术

One-pot, efficient synthesis of fused quinoline analogues via room temperature C(sp³)–N cleavage/aromatization reaction

Published:2024 Issue:4 Volume:48 Page:1489-1494
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Prasanna Kumari Subramaniyan¹,Thamotharan Subbiah²^ORCID,Selva Ganesan Subramaniapillai¹^ORCID

Affiliation:

1. Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur-613401, Tamil Nadu, India

2. Biomolecular Crystallography Laboratory, Department of Bioinformatics, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, 613401, Tamil Nadu, India

Abstract

One-pot transformation of N,N-dimethylaniline to fused quinoline derivatives was achieved through sequential oxidative cyclization followed by a concomitant C(sp3)–N cleavage/aromatization reaction.

Funder

Science and Engineering Research Board

Department of Biotechnology, Ministry of Science and Technology, India

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D3NJ05462D

Reference29 articles.

1. Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs – a review

2. Biologically active quinoline and quinazoline alkaloids part I

3. Development of drugs based on imidazole and benzimidazole bioactive heterocycles: recent advances and future directions

4. Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones

5. 1,3-Dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as potent caspase-3 inhibitors