A modular aldol approach for internal fluorescent molecular rotor chalcone surrogates for DNA biosensing applications-Reference-Cited by-同舟云学术

A modular aldol approach for internal fluorescent molecular rotor chalcone surrogates for DNA biosensing applications

Published:2023 Issue:18 Volume:14 Page:4832-4844
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Johnson Ryan E.¹,Murray Makay T.²,Bycraft Lucas J.¹,Wetmore Stacey D.²^ORCID,Manderville Richard A.¹^ORCID

Affiliation:

1. Department of Chemistry & Toxicology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada

2. Department of Chemistry & Biochemistry, University of Lethbridge, Lethbridge, Alberta, T1K 3M4, Canada

Abstract

Insertion of an indanone handle into DNA oligonucleotides permits base-catalyzed aldol to create fluorescent molecular rotor (FMR) chalcones with turn-on fluorescence and brightness suitable for biosensing applications.

Funder

Natural Sciences and Engineering Research Council of Canada

Canada Foundation for Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC00772C

Reference61 articles.

1. Fluorescent nucleobases as tools for studying DNA and RNA

2. Probing of Nucleic Acid Structures, Dynamics, and Interactions With Environment-Sensitive Fluorescent Labels

3. Rational design of small molecule fluorescent probes for biological applications

4. Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

5. Investigations on DNA intercalation and surface binding by SYBR Green I, its structure determination and methodological implications

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