Synthesis of illudalic acid and analogous phosphatase inhibitors

Author:

Fulo Harvey F.1ORCID,Rueb Nicole J.2,Gaston Robert1,Batsomboon Paratchata1ORCID,Ahmed Kh Tanvir1,Barrios Amy M.2ORCID,Dudley Gregory B.1ORCID

Affiliation:

1. C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, WV, 26506, USA

2. Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, 84112, USA

Abstract

A convergent 5-step synthesis (LLS) of illudalic acid allows for concise preparation of analogues for pharmacological evaluation.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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