Direct single-molecule detection of CoA-SH and ATP by the membrane proteins TMEM120A and TMEM120B

Author:

Zhao Changjian12,Chen Mutian12ORCID,Liu Xiaofeng3,Yuan Weidan1,Li Kaiju12,Wang Yu12,Chen Chen12,Zhang Ming1,Dong Yuhan12,Xiao Yuling1,Deng Dong3,Geng Jia12ORCID

Affiliation:

1. Department of Laboratory Medicine, State Key Laboratory of Biotherapy and Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan University, Chengdu, 610041, China

2. Tianfu Jincheng Laboratory, City of Future Medicine, Chengdu 610500, China

3. Division of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, 610041, Sichuan, China

Abstract

Membrane proteins are vital resources for developing biosensors.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Sichuan Province Science and Technology Support Program

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

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