Liposomes loaded with polyphenol-rich grape pomace extracts protect from neurodegeneration in a rotenone-based in vitro model of Parkinson's disease-Reference-Cited by-同舟云学术

Liposomes loaded with polyphenol-rich grape pomace extracts protect from neurodegeneration in a rotenone-based in vitro model of Parkinson's disease

Published:2021 Issue:24 Volume:9 Page:8171-8188
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Marino Attilio¹^ORCID,Battaglini Matteo¹,Desii Andrea¹,Lavarello Chiara²³,Genchi Giada¹,Petretto Andrea²,Ciofani Gianni¹^ORCID

Affiliation:

1. Istituto Italiano di Tecnologia, Smart Bio-Interfaces, Viale Rinaldo Piaggio 34, 56025 Pontedera, Italy

2. IRCCS Istituto Giannina Gaslini, Core Facilities-Clinical Proteomics and Metabolomics, Via Gerolamo Gaslini 5, 16147 Genova, Italy

3. University of Genoa, Department of Chemistry and Industrial Chemistry, Via Dodecaneso 31, 16146 Genova, Italy

Abstract

Liposomes were loaded with a polyphenol-rich extract from grape pomace. Liposomes successfully crossed the BBB and efficiently protected neural cells from neurodegeneration in relevant in vitro models.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01202A

Reference93 articles.

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2. The hallmarks of Parkinson's disease

3. Alpha-synuclein biology in Lewy body diseases

4. Ubiquitin–proteasome system and Parkinson's diseases

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