Binding uric acid: a pure chemical solution for the treatment of hyperuricemia-Reference-Cited by-同舟云学术

Binding uric acid: a pure chemical solution for the treatment of hyperuricemia

Published:2024 Issue:33 Volume:14 Page:24165-24174
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Yun-Yun¹,Li Jing²,Li Yan¹,Long Hong-Ping³,Lin Wei⁴,Wang Yi-Kun¹,Tang Rong⁵,Liu Xue-Wu⁶,Jiang Dejian⁶,Liu Shao²,Cao Dongsheng¹^ORCID,Tan Gui-Shan²,Xu Kang-Ping¹,Wang Wen-Xuan¹⁶^ORCID

Affiliation:

1. Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410008, PR China

2. Department of Pharmacy, National Clinical Research Center for Geriatric Disorder, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China

3. The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, PR China

4. Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China

5. Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, PR China

6. Hunan Prima Drug Research Center Co., Ltd, Hunan Research Center for Drug Safety Evaluation, Hunan Key Laboratory of Pharmacodynamics and Safety Evaluation of New Drugs, Changsha, Hunan 410331, PR China

Abstract

A binding partner designed for uric acid inhibits its precipitation and ionization, and shows an anti-hyperuricemia activity in vivo competitive with benzbromarone, as well as a favorable safety profile.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Key Research and Development Program of Hunan Province of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04626A

Reference32 articles.

1. Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation

2. Uric acid and chronic kidney disease: which is chasing which?

3. Impact of Hyper- and Hypo-Uricemia on Kidney Function

4. Uric Acid and Cardiovascular Risk

5. The Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation