Exploring polymorphism, stoichiometric diversity and simultaneous existence of salt and cocrystal during cocrystallization using mechanochemistry

Author:

Gogoi Diptajyoti1,Kalita Kalyan J.2,Biswakarma Nishant3,Arhangelskis Mihails4ORCID,Deka Ramesh Ch3ORCID,Thakuria Ranjit1ORCID

Affiliation:

1. Department of Chemistry, Gauhati University, Guwahati 781014, India

2. Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, 741246, West Bengal, India

3. Department of Chemical Sciences, Tezpur University, Tezpur, Assam, India

4. Faculty of Chemistry, University of Warsaw, 1 Pasteura Street, 02-093 Warsaw, Poland

Abstract

We demonstrate here the mechanochemical cocrystallization of trans-aconitic acid with nicotinamide that resulted salt and cocrystal forms with stoichiometric diversity, polymorphism and high Z′′.

Funder

Science and Engineering Research Board

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

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