Aromadendrin: a dual amyloid promoter to accelerate fibrillization and reduce cytotoxicity of both amyloid-β and hIAPP

Author:

Zhang Yanxian1234ORCID,Zhang Dong1234ORCID,Tang Yijing1234,Ren Baiping1234,Liu Fufeng56789ORCID,Xu Lijian101112139,Chang Yung14151617ORCID,Zheng Jie1234ORCID

Affiliation:

1. Department of Chemical, Biomolecular, and Corrosion Engineering

2. The University of Akron

3. Ohio

4. USA

5. Key Laboratory of Industrial Fermentation Microbiology

6. College of Biotechnology

7. Tianjin University of Science & Technology

8. Tianjin 300457

9. China

10. Hunan Key Laboratory of Biomedical Nanomaterials and Devices

11. College of Life Science and Chemistry

12. Hunan University of Technology

13. Zhuzhou 412007

14. Department of Chemical Engineering and R&D Center for Membrane Technology

15. Chung Yuan Christian University

16. Taoyuan 320

17. Taiwan

Abstract

Aromadendrin, as a protective amyloid promoter, is discovered to simultaneously promote the aggregation of Aβ and hIAPP peptides and reduce the amyloid-induced cytotoxicity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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