Enhanced anti-cancer efficacy to cancer cells by a novel monofunctional mononuclear platinum(ii) complex containing a mixed S,N,S-donor ligand-Reference-Cited by-同舟云学术

Enhanced anti-cancer efficacy to cancer cells by a novel monofunctional mononuclear platinum(ii) complex containing a mixed S,N,S-donor ligand

Published:2017 Issue:14 Volume:41 Page:6760-6768
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Chen Zhanfen¹²³⁴⁵^ORCID,Zhang Shuping⁶⁷⁸⁹,Zhang Jian⁶⁷⁸⁹,Zhu Zhenzhu¹⁰¹¹¹²¹³⁹

Affiliation:

1. Flexible Display Mater. & Tech. Co-Innovation Center of Hubei

2. Key Laboratory of Optoelectronic Chemical Materials and Devices of Ministry of Education

3. School of Chemistry and Environmental Engineering

4. Jianghan University

5. Wuhan 430056

6. College of Chemistry & Chemical Engineering

7. Hubei Normal University

8. Huangshi 435002

9. P. R. China

10. State Key Laboratory of Coordination Chemistry

11. School of Chemistry and Chemical Engineering

12. Nanjing University

13. Nanjing 210017

Abstract

A novel platinum–intercalator hybrid complex (1) exhibits a cytotoxicity comparable to that of cisplatin against MCF-7 cell lines, and more potent activities against HeLa and A-549 cell lines, especially against the former.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ01472D

Reference65 articles.

1. Structure, Recognition, and Processing of Cisplatin−DNA Adducts

2. The resurgence of platinum-based cancer chemotherapy

3. Fresh Platinum Complexes with Promising Antitumor Activity

4. Synthetic Methods for the Preparation of Platinum Anticancer Complexes

5. DNA Metalating-Intercalating Hybrid Agents for the Treatment of Chemoresistant Cancers

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