Synthesis of nicotinimidamides <i>via</i> a tandem CuAAC/ring-cleavage /cyclization/oxidation four-component reaction and their cytotoxicity-Reference-Cited by-同舟云学术

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Synthesis of nicotinimidamides via a tandem CuAAC/ring-cleavage /cyclization/oxidation four-component reaction and their cytotoxicity

Published:2024 Issue:35 Volume:14 Page:25844-25851
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chen Xi¹,Li Guanrong²,Huang Zixin²,Luo Qiaoli³,Chen Tao¹,Yang Weiguang²^ORCID

Affiliation:

1. Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China

2. School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, Guangdong, 524023, China

3. School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang, 524048, P. R. China

Abstract

An efficient tandem CuAAC/ring-cleavage/cyclization/oxidation four-component reaction for the synthesis of nicotinimidamides, and the cytotoxicity of nicotinimidamide was also tested.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04918G

Reference51 articles.

1. Pyridine elaboration through organometallic intermediates: regiochemical control and completeness

2. Michael Addition with an Olefinic Pyridine: Organometallic Nucleophiles and Carbon Electrophiles

3. Organometallic Intermediates in the Synthesis of Photoluminescent Zirconium and Hafnium Complexes with Pyridine Dipyrrolide Ligands

4. Recent advances in sustainable N-heterocyclic carbene-Pd(II)-pyridine (PEPPSI) catalysts: A review

5. Contribution to the Synthesis, Characterization, Separation and Quantification of New N-Acyl Thiourea Derivatives with Antimicrobial and Antioxidant Potential

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