A mitochondria-targeted fluorescent probe based on coumarin–pyridine derivatives for hypochlorite imaging in living cells and zebrafish
Author:
Affiliation:
1. Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
2. Jiangsu Key Laboratory of Bio-functional Materials
3. School of Chemistry and Materials Science
4. Nanjing Normal University
5. Nanjing 210023
Abstract
Herein, a novel coumarin–pyridine derivative (CPD) was prepared and exhibited a rapid response, large Stokes shifts, dual channel detection, high selectivity and high sensitivity toward OCl− in mitochondria of A549 cells and zebrafish.
Funder
Priority Academic Program Development of Jiangsu Higher Education Institutions
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB01948K
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