Human cytochrome P450 enzyme inhibition profile of three flavonoids isolated from Psoralea corylifolia: in silico predictions and experimental validation-Reference-Cited by-同舟云学术

Human cytochrome P450 enzyme inhibition profile of three flavonoids isolated from Psoralea corylifolia: in silico predictions and experimental validation

Published:2018 Issue:13 Volume:42 Page:10922-10934
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Wang Lili¹²³⁴²,Hai Yue¹²³,Huang Nannan¹²³,Gao Xue¹²³,Liu Wenli¹²³,He Xin¹²³⁴²^ORCID

Affiliation:

1. Tianjin University of Traditional Chinese Medicine

2. Tianjin

3. P. R. China

4. Tianjin State Key Laboratory of Modern Chinese Medicine

Abstract

Cytochrome P450 enzyme (CYP)-associated metabolic studies in vitro have been considered cost-effective for predicting potential clinical drug/herb–drug interactions (DDI/HDI).

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C7NJ00884H

Reference31 articles.

1. Cytochromes P450, Drugs, and Diseases

2. In Silico Prediction of Drug Properties

3. Molecular Dynamics-Based Virtual Screening: Accelerating the Drug Discovery Process by High-Performance Computing

4. Mechanism of CYP2C9 Inhibition by Flavones and Flavonols

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