The cytotoxic potential of cationic triangulenes against tumour cells-Reference-Cited by-同舟云学术

The cytotoxic potential of cationic triangulenes against tumour cells

Published:2019 Issue:11 Volume:10 Page:1881-1891
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Leung Euphemia¹²³⁴^ORCID,Pilkington Lisa I.⁵²⁶⁴^ORCID,Naiya Mohinder M.⁵²⁶⁴,Barker David⁵²⁶⁴^ORCID,Zafar Ayesha⁵²⁶⁴,Eurtivong Chatchakorn⁷⁸⁹¹⁰¹¹^ORCID,Reynisson Jóhannes⁵²⁶⁴¹²^ORCID

Affiliation:

1. Auckland Cancer Society Research Centre

2. University of Auckland

3. Auckland 1023

4. New Zealand

5. School of Chemical Sciences

6. Auckland 1010

7. Program of Chemical Biology

8. Chulabhorn Graduate Institute

9. Chulabhorn Royal Academy of Science

10. Bangkok 10210

11. Thailand

12. School of Pharmacy

Abstract

Close-shelled carbocations DNA intercalators Pr-ADOTA and Pr-DAOTA are very cytotoxic against the cancer cell lines MDA-MB-231 (breast) and HCT116 (colon).

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00305C

Reference55 articles.

1. Vibrational spectroscopic and quantum chemical studies of the trioxatriangulenium carbocation

2. Intercalation of Trioxatriangulenium Ion in DNA: Binding, Electron Transfer, X-ray Crystallography, and Electronic Structure

3. Photo-oxidation of duplex DNA with the stable trioxatriangulenium ion

4. Duplex and Quadruplex DNA Binding and Photocleavage by Trioxatriangulenium Ion

5. Photophysics of trioxatriangulenium ion. Electrophilic reactivity in the ground state and excited singlet state

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