Silica-coated LiYF4:Yb3+, Tm3+ upconverting nanoparticles are non-toxic and activate minor stress responses in mammalian cells

Author:

Bietar Kais1ORCID,Chu Siwei1ORCID,Mandl Gabrielle2ORCID,Zhang Emma1ORCID,Chabaytah Naim1ORCID,Sabelli Renata1,Capobianco John A.2ORCID,Stochaj Ursula13ORCID

Affiliation:

1. Department of Physiology, McGill University, Canada

2. Department of Chemistry and Biochemistry, Centre for Nanoscience Research, Concordia University, Canada

3. Quantitative Life Sciences Program, McGill University, Montreal, Canada

Abstract

Silica-coated lanthanide-doped upconverting nanoparticles (UCNPs) are internalized by mammalian cells. The bipyramidal UCNPs are non-toxic and elicit minor stress responses in a cell type-dependent fashion.

Funder

Fonds de recherche du Québec – Nature et technologies

McGill University

Mitacs

Fonds de Recherche du Québec - Santé

Natural Sciences and Engineering Research Council of Canada

Concordia University

Publisher

Royal Society of Chemistry (RSC)

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