A bioluminescent probe for NQO1 overexpressing cancer cell imaging <i>in vitro</i> and <i>in vivo</i>-Reference-Cited by-同舟云学术

A bioluminescent probe for NQO1 overexpressing cancer cell imaging in vitro and in vivo

Published:2022 Issue:23 Volume:147 Page:5264-5268
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Luo Yuhong¹^ORCID,Wang Wentao¹,Zeng Yi²^ORCID,Wang Shuangqing¹^ORCID,Guo Xudong¹,Hu Rui¹^ORCID,Yang Guoqiang¹^ORCID

Affiliation:

1. Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Photochemistry, Institute of Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, China

2. Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, China

Abstract

A bioluminescent probe NQO1-Luc toward NQO1 was constructed, which exhibits high selectivity and sensitivity toward NQO1 in vitro and adequate capability of distinguishing NQO1-overexpressing tumors in vivo.

Funder

Youth Innovation Promotion Association of the Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN01435A

Reference34 articles.

1. Aggregation Enhanced Responsiveness of Rationally Designed Probes to Hydrogen Sulfide for Targeted Cancer Imaging

2. Activatable Molecular Probes for Cancer Imaging