Lutein combined with EGCG improved retinitis pigmentosa against <i>N</i>-methyl-<i>N</i> nitrosourea-induced-Reference-Cited by-同舟云学术

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Lutein combined with EGCG improved retinitis pigmentosa against N-methyl-N nitrosourea-induced

Published:2023 Issue:21 Volume:14 Page:9554-9566
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jing Huili¹²,Nie Meimei¹,Wang Xiaoqin¹²,Zhang Zhongyuan¹^ORCID,Xu Yayuan¹,Zhang Guodong³,Li Dajing¹²,Dai Zhuqing¹²^ORCID

Affiliation:

1. Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China

2. School of Food and Biological Engineering, Jiangsu University, Zhenjiang, 212013, China

3. Jiangsu Aland Nutrition Co., Ltd, Taizhou 214500, China

Abstract

Dietary LUT combined with EGCG increase the thickness of outer nuclear layer of retina, up-regulate the expression of anti-apoptotic genes, affect the content of short-chain fatty acids and regulate the structure of gut microbiota, thus improving the retinal structure of MNU-induced RP mice.

Funder

National Natural Science Foundation of China

Jiangsu Provincial Key Research and Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO02716C

Reference47 articles.

1. The Role of Inflammation in Retinal Neurodegeneration and Degenerative Diseases

2. Nutraceutical Supplementation Ameliorates Visual Function, Retinal Degeneration, and Redox Status in rd10 Mice

3. Corneal characteristics in patients with retinitis pigmentosa

4. Retinitis Pigmentosa

5. The intestinal microbiome and health

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