Exploitation of the multitarget role of new ferulic and gallic acid derivatives in oxidative stress-related Alzheimer's disease therapies: design, synthesis and bioevaluation-Reference-Cited by-同舟云学术

Exploitation of the multitarget role of new ferulic and gallic acid derivatives in oxidative stress-related Alzheimer's disease therapies: design, synthesis and bioevaluation

Published:2024 Issue:15 Volume:14 Page:10304-10321
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hussain Fahad¹,Tahir Ayesha¹,Jan Muhammad Saeed²^ORCID,Fatima Noor¹,Sadiq Abdul³,Rashid Umer¹^ORCID

Affiliation:

1. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, 22060 Abbottabad, Pakistan

2. Department of Pharmacy, Bacha Khan University, 24420, Charsadda, KPK, Pakistan

3. Department of Pharmacy, University of Malakand, 18000 Chakdara, KP, Pakistan

Abstract

Monoamine oxidases (MAOs) inhibitors could decrease reactive oxygen species (ROS) generation, enhance mono-aminergic neural transmission, and have major therapeutic benefits for the treatment of Alzheimer's disease (AD).

Funder

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00766B

Reference61 articles.

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3. Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer’s Disease

4. Clinical aspects of Alzheimer's disease

5. Neuroprotection and neurodegenerative disease

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