Extraction of small extracellular vesicles by label-free and biocompatible on-chip magnetic separation-Reference-Cited by-同舟云学术

Extraction of small extracellular vesicles by label-free and biocompatible on-chip magnetic separation

Published:2022 Issue:13 Volume:22 Page:2476-2488
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Zeng Lin¹,Hu Shi¹,Chen Xi¹,Zhang Pengcheng¹,Gu Guoqiang¹,Wang Yuye¹,Zhang Hongpeng²,Zhang Yi³,Yang Hui¹⁴^ORCID

Affiliation:

1. Laboratory of Biomedical Microsystems and Nano Devices, Bionic Sensing and Intelligence Center, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 518055 Shenzhen, China

2. Marine Engineering College, Dalian Maritime University, 116026 Dalian, China

3. Center for Medical AI, Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 518055 Shenzhen, China

4. CAS Key Laboratory of Health Informatics, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 518055 Shenzhen, China

Abstract

Small vesicles (sEVs) are closely related to many diseases as they carry various bio-markers. A label-free and biocompatible on-chip separation method based on negative magnetophoresis is presented for the extraction of sEVs.

Funder

National Natural Science Foundation of China

Special Project for Research and Development in Key areas of Guangdong Province

Basic and Applied Basic Research Foundation of Guangdong Province

Shenzhen Institutes of Advanced Technology Innovation Program for Excellent Young Researchers

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00217E