A new method for peptide synthesis in the N→C direction: amide assembly through silver-promoted reaction of thioamides-Reference-Cited by-同舟云学术

A new method for peptide synthesis in the N→C direction: amide assembly through silver-promoted reaction of thioamides

Published:2014 Issue:100 Volume:50 Page:15963-15966
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Pourvali Aysa¹²³,Cochrane James R.¹²³,Hutton Craig A.¹²³

Affiliation:

1. School of Chemistry and Bio21 Molecular Science and Biotechnology Institute

2. University of Melbourne

3. , Australia

Abstract

The Ag(i)-promoted coupling of peptide-acids with thioamides generates peptide-imides, which was exploited in the synthesis of peptides in the N→C direction.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC07601J

Reference35 articles.

1. Rethinking amide bond synthesis

2. Amide bond formation: beyond the myth of coupling reagents

3. Evolution of amide bond formation

4. A Fascinating Journey into History: Exploration of the World of Isonitriles En Route to Complex Amides

5. Direct Synthesis of Amides from Alcohols and Amines with Liberation of H 2

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