Photosubstitution and photoreduction of a diazido platinum(<scp>iv</scp>) anticancer complex-Reference-Cited by-同舟云学术

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Photosubstitution and photoreduction of a diazido platinum(iv) anticancer complex

Published:2024 Issue:31 Volume:53 Page:13044-13054
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Shi Huayun¹^ORCID,Ward-Deitrich Christian²^ORCID,Ponte Fortuna³^ORCID,Sicilia Emilia³^ORCID,Goenaga-Infante Heidi²^ORCID,Sadler Peter J.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK

2. LGC Limited, National Measurement Laboratory (NML), Queens Road, Teddington, Middlesex TW11 0LY, UK

3. Department of Chemistry and Chemical Technologies, University of Calabria, via Pietro Bucci, 87036 Arcavacata di Rende, Cs, Italy

Abstract

HPLC-ICPMS with LC-MS allows identification of products from photoactivation of a diazido Pt(iv) anticancer complex by visible light under physiologically-relevant conditions, including novel polyhyroxido Pt(iv) species, potential pharmacophores.

Funder

Engineering and Physical Sciences Research Council

Associazione Italiana per la Ricerca sul Cancro

Università della Calabria

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT01587H

Reference54 articles.

1. Cisplatin: The first metal based anticancer drug

2. Platinum-based drugs for cancer therapy and anti-tumor strategies

3. The rediscovery of platinum-based cancer therapy

4. What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives

5. Diazido platinum(iv) complexes for photoactivated anticancer chemotherapy

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