Ruthenium(ii) arene complexes containing benzhydrazone ligands: synthesis, structure and antiproliferative activity-Reference-Cited by-同舟云学术

Ruthenium(ii) arene complexes containing benzhydrazone ligands: synthesis, structure and antiproliferative activity

Published:2016 Issue:10 Volume:3 Page:1245-1255
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Subarkhan Mohamed Kasim Mohamed¹²³⁴⁵,Ramesh Rengan¹²³⁴⁵

Affiliation:

1. Centre for Organometallic Chemistry

2. School of Chemistry

3. Bharathidasan University

4. Tiruchirappalli 620 024

5. India

Abstract

Six new Ru(ii) arene anthracene benzhydrazone complexes have been synthesized and show excellent cytotoxicity against human cancer cell lines. The results of apoptosis assays demonstrated that complexes4and6are able to induce apoptosis in human cancer cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/QI/C6QI00197A

Reference71 articles.

1. The resurgence of platinum-based cancer chemotherapy

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4. Approaching tumour therapy beyond platinum drugs

5. Mechanisms of platinum drug resistance

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