New triterpenes from Cimicifuga yunnanensis down-regulating the mRNA expression of CD147, MMP-2, and MMP-9-Reference-Cited by-同舟云学术

New triterpenes from Cimicifuga yunnanensis down-regulating the mRNA expression of CD147, MMP-2, and MMP-9

Published:2021 Issue:58 Volume:11 Page:36978-36988
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lu Ni-Hong¹,Li Jie¹,Yang Yong-Rui¹,Liu Hong-Lu¹,Du Ying-Rong¹^ORCID

Affiliation:

1. Department of Respiratory Medicine, The Third People's Hospital of Kunming, Yunnan, 650041, People's Republic of China

Abstract

Eleven new 9,19-cycloartane triterpenes (CTs) (1–9, 11–12) and one undescribed lanostane-type aglycone (10) were identified from Cimicifuga yunnanensis. CTs aglycones 7 and 8 potently down-regulated the mRNA expression of CD147, MMP-2, and MMP-9.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA07828C

Reference33 articles.

1. Clinical Advances in Immunonutrition and Atherosclerosis: A Review

2. Demographic and Epidemiologic Drivers of Global Cardiovascular Mortality

3. Atherosclerosis — An Inflammatory Disease

4. Extracellular Matrix Metalloproteinase Inducer Regulates Matrix Metalloproteinase Activity in Cardiovascular Cells

5. Identification of 92-kD Gelatinase in Human Coronary Atherosclerotic Lesions

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