A microfluidic platform for functional testing of cancer drugs on intact tumor slices-Reference-Cited by-同舟云学术

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A microfluidic platform for functional testing of cancer drugs on intact tumor slices

Published:2020 Issue:9 Volume:20 Page:1658-1675
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Rodriguez A. D.¹²³⁴^ORCID,Horowitz L. F.¹²³⁴⁵,Castro K.¹²³⁴,Kenerson H.⁶⁷⁴,Bhattacharjee N.¹²³⁴^ORCID,Gandhe G.¹²³⁴,Raman A.¹²³⁴,Monnat R. J.⁵²³⁴,Yeung R.⁶⁷⁴,Rostomily R. C.⁸⁹¹⁰⁴⁸,Folch A.¹²³⁴

Affiliation:

1. Department of Bioengineering

2. University of Washington

3. Seattle

4. USA

5. Department of Pathology

6. Department of Surgery

7. University of Washington Seattle

8. Department of Neurosurgery

9. Houston Methodist Hospital and Research Institute

10. Houston

Abstract

We have developed a digitally-manufacturable microfluidic platform that allows for multiplexed drug testing of intact tumor slices.

Funder

National Cancer Institute

U.S. Department of Defense

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00811J

Reference70 articles.

1. The High Cost of Cancer Drugs and What We Can Do About It

2. Phase II and phase III failures: 2013–2015

3. Are animal models predictive for humans?

4. Functional precision cancer medicine—moving beyond pure genomics

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