Packaging of DNA origami in viral capsids: towards synthetic viruses-Reference-Cited by-同舟云学术

Packaging of DNA origami in viral capsids: towards synthetic viruses

Published:2022 Issue:32 Volume:14 Page:11535-11542
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kler Stanislav¹,Zalk Ran²,Upcher Alexander²,Kopatz Idit¹^ORCID

Affiliation:

1. Geza Ad Ltd, Givatayim 53251, Israel

2. Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer Sheva, 84105, Israel

Abstract

We report a new type of nanoparticle for gene delivery, consisting of a nucleic acid core (>7500 nt) folded into a 35 nm DNA origami sphere, encapsulated by a capsid composed of the three SV40 virus capsid proteins.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR01316A

Reference56 articles.

1. Towards synthetic viruses

2. Advances in Lipid Nanoparticles for mRNA-Based Cancer Immunotherapy

3. Synthetic Gene Transfer Vectors II: Back to the Future.

4. M.Ericsona , K.Ricea and G.Zuberb , Macromolecular Conjugates for Non-Viral Nucleic Acid Delivery , in Advanced Textbook On Gene Transfer, Gene Therapy And Genetic Pharmacology: Principles, Delivery And Pharmacological And Biomedical Applications Of Nucleotide-based Therapies , 2019 , p. 223

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dominant Analytical Techniques in DNA Nanotechnology for Various Applications;Analytical Chemistry;2024-02-14

2. Specific interaction based drug loading strategies;Nanoscale Horizons;2023