Hyperpatone A, a polycyclic polyprenylated acylphloroglucinol with a rare 8/6/5/6/5 pentacyclic skeleton from <i>Hypericum patulum</i>-Reference-Cited by-同舟云学术

Hyperpatone A, a polycyclic polyprenylated acylphloroglucinol with a rare 8/6/5/6/5 pentacyclic skeleton from Hypericum patulum

Published:2023 Issue:1 Volume:21 Page:140-146
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Feng¹²³,Yang Jue¹²³,Yi Ping¹²³,Li Ya-Nan¹²³,Hao Xiao-Jiang¹²³⁴^ORCID,Yuan Chun-Mao¹²³^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, People's Republic of China

2. School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang 550025, China

3. The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550014, China

4. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China

Abstract

Hyperpatone A (1), a highly oxidated polycyclic polyprenylated acylphloroglucinol (PPAP), with good cytotoxic and anti-flammatory activities was isolated from Hypericum patulum under the guidance of LC-MS investigation.

Funder

National Natural Science Foundation of China

Guizhou Science and Technology Department

Guizhou Education Department Youth Science and Technology Talents Growth Project

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB01851A

Reference33 articles.

1. And then came molecular phylogenetics—Reactions to a monographic study of Hypericum (Hypericaceae)

2. P. F.Stevens , Flowering Plants Eudicots , Springer , Berlin, Heidelberg , 2007 , pp. 48–66

3. Structural diversity and biological activities of phloroglucinol derivatives from Hypericum species

4. Recent Advances Regarding Constituents and Bioactivities of Plants from the GenusHypericum

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Spirohypertones A and B as potent antipsoriatics: Tumor necrosis factor-α inhibitors with unprecedented chemical architectures;Acta Pharmaceutica Sinica B;2024-06

2. Discovery of adamantane-type polycyclic polyprenylated acylphloroglucinols that can prevent concanavalin A-induced autoimmune hepatitis in mice;Bioorganic Chemistry;2024-03