Construction of a spiro[pyrazolone-4,2′-pyridoindole] scaffold via a [3 + 3] cycloaddition of 2-indolylmethanol with a 4-aminopyrazolone-derived azomethine ylide-Reference-Cited by-同舟云学术

Construction of a spiro[pyrazolone-4,2′-pyridoindole] scaffold via a [3 + 3] cycloaddition of 2-indolylmethanol with a 4-aminopyrazolone-derived azomethine ylide

Published:2021 Issue:39 Volume:19 Page:8530-8538
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Nawaz Shah¹²,Huang Yue¹,Bao Xiaoze¹,Wei Shiqiang¹,Wei Xingfu¹,Qu Jingping¹^ORCID,Wang Baomin¹^ORCID

Affiliation:

1. State Key Laboratory of Fine Chemicals, Department of Pharmaceutical Sciences, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, People's Republic of China

2. Department of Chemistry, Karakoram International University, Gilgit-Baltistan, 15100, Pakistan

Abstract

A one-pot [3 + 3] cycloaddition of 2-indolylmethanol with an in situ generated azomethine ylide derived from 4-aminopyrazolone is developed to access the spiro[pyrazolone–pyridoindole] scaffold.

Funder

Central University Basic Research Fund of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01631H

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