Preparation and characterization of layer-by-layer hypoglycemic nanoparticles with pH-sensitivity for oral insulin delivery-Reference-Cited by-同舟云学术

Preparation and characterization of layer-by-layer hypoglycemic nanoparticles with pH-sensitivity for oral insulin delivery

Published:2018 Issue:45 Volume:6 Page:7451-7461
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhang Li¹²³⁴⁵^ORCID,Qin Han¹²³⁶⁷^ORCID,Li Jian⁸²³^ORCID,Qiu Jia-Ni¹²³⁶⁷^ORCID,Huang Jing-Min¹²³⁶⁷^ORCID,Li Ming-Chao¹²³⁶⁷^ORCID,Guan Yan-Qing¹²³⁶⁷^ORCID

Affiliation:

1. School of Life Science, South China Normal University

2. Guangzhou 510631

3. China

4. National Engineering Research Center for Healthcare Devices, Guangdong Key Lab of Medical Electronic Instruments and Polymer Material Products, Guangdong Institute of Medical Instruments

5. Guangzhou 510500

6. Institute for Advanced Materials and Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials South China Academy of Advanced Optoelectronics, South China Normal University

7. Guangzhou 510006

8. MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University

Abstract

We developed an insulin oral delivery system with the combination of pH-sensitive material and structure to avoid intestinal degradation.

Funder

National Natural Science Foundation of China

Guangzhou Municipal Science and Technology Project

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2018/TB/C8TB02113A

Reference62 articles.

1. Preparation and characterization of insulin-loaded bioadhesive PLGA nanoparticles for oral administration

2. Insulin delivery methods: Past, present and future

3. Why most oral insulin formulations do not reach clinical trials

4. Insight into the interactions between nanoparticles and cells

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