Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics-Reference-Cited by-同舟云学术

Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics

Published:2022 Issue:32 Volume:12 Page:20432-20446
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

O'Sullivan Joseph¹^ORCID,Muñoz-Muñoz Jose¹,Turnbull Graeme¹^ORCID,Sim Neil²,Penny Stuart²,Moschos Sterghios¹^ORCID

Affiliation:

1. Department of Applied Sciences, Northumbria University, Newcastle upon Tyne, UK, NE1 8ST

2. High Force Research Ltd, Bowburn North Industrial Estate, Durham, UK, DH6 5PF

Abstract

Tapping the glycome space for targeted delivery. We explore GalNAc for targeting oligonucleotides to the liver and ask what other oligosaccharides could expand targeting options for other tissues.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA01999J

Reference189 articles.

1. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis

2. Huntington disease: a single-gene degenerative disorder of the striatum

3. Nucleic Acid Therapeutics for Neurological Diseases

4. Cell-penetrating-peptide-mediated siRNA lung delivery

5. The Clinical Potential of Oligonucleotide Therapeutics against Pancreatic Cancer

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current status and trends in small nucleic acid drug development: Leading the future;Acta Pharmaceutica Sinica B;2024-09

2. Dual-targeting galactose-functionalized hyaluronic acid modified lipid nanoparticles delivering silybin for alleviating alcoholic liver injury;International Journal of Pharmaceutics;2024-09

3. Synthesis and biological evaluation of a novel 68Ga-labeled GalNAc-PET probe for asialoglycoprotein receptor imaging;Colloids and Surfaces A: Physicochemical and Engineering Aspects;2024-08

4. Advancing Liver Gene Therapy: Enhanced Transduction with GalNAc-Bioconjugated rAAV Capsids;2024-07-25

5. Messenger RNA-Based Therapeutics and Vaccines: What’s beyond COVID-19?;ACS Pharmacology & Translational Science;2023-07-03