One-shot high-resolution melting curve analysis for KRAS point-mutation discrimination on a digital microfluidics platform-Reference-Cited by-同舟云学术

One-shot high-resolution melting curve analysis for KRAS point-mutation discrimination on a digital microfluidics platform

Published:2022 Issue:3 Volume:22 Page:537-549
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Li Mingzhong¹,Wan Liang¹²,Law Man-Kay¹²^ORCID,Meng Li¹²,Jia Yanwei¹²^ORCID,Mak Pui-In¹²,Martins Rui P.¹²³

Affiliation:

1. State Key Laboratory of Analog and Mixed-Signal VLSI, Institute of Microelectronics, University of Macau, Taipa, Macao, China

2. Faculty of Science and Technology – Electrical and Computer Engineering, University of Macau, Macao, China

3. On leave from Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal

Abstract

Proposed high-accuracy one-shot melting curve analysis on a digital microfluidics platform, enabling KRAS gene discrimination with single-nucleotide mutations in 3 seconds.

Funder

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Universidade de Macau

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC00564B

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