Photochemical study of the highly used corticosteroids dexamethasone and prednisone. Effects of micellar confinement and cytotoxicity analysis of photoproducts-Reference-Cited by-同舟云学术

Photochemical study of the highly used corticosteroids dexamethasone and prednisone. Effects of micellar confinement and cytotoxicity analysis of photoproducts

Published:2020 Issue:42 Volume:44 Page:18119-18129
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Cacciari R. Daniel¹²³⁴⁵,Reynoso Eugenia¹²³⁴⁵,Candela Florencia Menis⁶³⁷⁸⁹,Sabini Carola⁶³⁷⁸⁹,Montejano Hernán A.¹²³⁴⁵,Biasutti M. Alicia¹²³⁴⁵^ORCID

Affiliation:

1. Departamento de Química

2. Facultad de Ciencias Exactas

3. Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto

4. Ruta Nacional 36 Km 601

5. X5804BYA Río Cuarto

6. Departamento de Microbiología, Facultad de Ciencias Exactas

7. Ruta Nacional 36 Km 601, X5804BYA Río Cuarto

8. Córdoba

9. Argentina

Abstract

Photodegradation of dexamethasone (Dexa) and prednisone (Pred) occurs by a combination of ROS attack and unimolecular photodegradation reactions. The photoproducts obtained are more cytotoxic than the parent compounds.

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Universidad Nacional de Río Cuarto

Secretaría de Ciencia y Técnica, Universidad Nacional de Río Cuarto

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ03640D

Reference56 articles.

1. Front cover