Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings-Reference-Cited by-同舟云学术

Topologically controlled circuits of human iPSC-derived neurons for electrophysiology recordings

Published:2022 Issue:7 Volume:22 Page:1386-1403
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Girardin Sophie¹,Clément Blandine¹,Ihle Stephan J.¹,Weaver Sean¹^ORCID,Petr Jana B.¹^ORCID,Mateus José C.²^ORCID,Duru Jens¹,Krubner Magdalena¹,Forró Csaba³,Ruff Tobias¹,Fruh Isabelle⁴,Müller Matthias⁴,Vörös János¹^ORCID

Affiliation:

1. Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, ETH Zurich, Gloriastrasse 35, 8092 Zurich, Switzerland

2. Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, Porto, Portugal

3. Cui Laboratory, S285 290 Jane Stanford Way Stanford, Stanford, CA 94305, USA

4. Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, 4002 Basel, Switzerland

Abstract

We present a method to build microcircuits of human induced pluripotent stem cell (iPSC)-derived neurons with a controlled topology. The circuits are compatible with imaging and microelectrode array experiments.

Funder

Eidgenössische Technische Hochschule Zürich

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC01110C

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1. “Brains on a chip”: Towards engineered neural networks

2. Breaking the neural code