Room temperature ligand-free Cu2O–H2O2 catalyzed tandem oxidative synthesis of quinazoline-4(3H)-one and quinazoline derivatives-Reference-Cited by-同舟云学术

Room temperature ligand-free Cu₂O–H₂O₂ catalyzed tandem oxidative synthesis of quinazoline-4(3H)-one and quinazoline derivatives

Published:2023 Issue:4 Volume:21 Page:748-753
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Dutta Nilakshi¹^ORCID,Dutta Bidyutjyoti¹^ORCID,Dutta Apurba²^ORCID,Sarma Bipul³^ORCID,Sarma Diganta¹^ORCID

Affiliation:

1. Department of Chemistry, Dibrugarh University, Dibrugarh-786004, Assam, India

2. Department of Chemistry, DHSK College, Dibrugarh-786001, Assam, India

3. Department of Chemical Sciences, Tezpur University, Tezpur-784028, Assam, India

Abstract

A simple and efficient ligand-free copper catalytic protocol has been developed for the synthesis of quinazolinone and quinazoline derivatives in the presence of KOH–DMSO. The use of green oxidant H2O2 enhances the significance of the protocol.

Funder

Department of Biotechnology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02085H

Reference67 articles.

1. Copper-catalyzed annulation of amidines for quinazoline synthesis

2. AN ALKALOID WITH HIGH ANTIMALARIAL ACTIVITY FROM DICHROA FEBRIFUGA1

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4. The chemistry of recently isolated naturally occurring quinazolinone alkaloids

5. Synthesis of quinazolinones and quinazolines

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