Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β-Reference-Cited by-同舟云学术

Impact of sphingosine and acetylsphingosines on the aggregation and toxicity of metal-free and metal-treated amyloid-β

Published:2021 Issue:7 Volume:12 Page:2456-2466
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yi Yelim¹²³⁴,Lin Yuxi⁵⁶⁷⁴,Han Jiyeon¹²³⁴,Lee Hyuck Jin⁸⁹¹⁰⁴^ORCID,Park Nahye¹¹¹¹²⁴,Nam Geewoo¹¹¹¹²⁴,Park Young S.¹¹¹¹²⁴^ORCID,Lee Young-Ho⁵⁶⁷⁴¹³,Lim Mi Hee¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Korea Advanced Institute of Science and Technology (KAIST)

3. Daejeon 34141

4. Republic of Korea

5. Research Center of Bioconvergence Analysis

6. Korea Basic Science Institute (KBSI)

7. Ochang

8. Department of Chemistry Education

9. Kongju National University

10. Gongju 32588

11. Ulsan National Institute of Science and Technology (UNIST)

12. Ulsan 44919

13. Research Headquarters

Abstract

The reactivity of sphingosine and acetylsphingosines towards both metal-free and metal-treated amyloid-β is demonstrated showing a correlation of their micellization properties.

Funder

National Research Foundation of Korea

National Research Council of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC04366D

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